Perspectives on Classification of Brain Injuries
Dan Lewis Foundation | Spring 2023

The medical care and medical research fields have traditionally classified brain injuries as either Acquired Brain Injuries (ABIs) or Traumatic Brain Injuries (TBIs). From a broad perspective, all brain injuries are “acquired,” except congenital disorders. But the terms ABI and TBI have each, over time, taken on specific definitions with different implications, which are discussed here.


The term ABI is usually applied to injuries caused by a wide range of factors including strokes, infections, tumors, anoxia (lack of oxygen to the brain, for instance, from drowning or choking), neurotoxic poisoning, drug overdose, aneurysms, seizures, electric shock, and other factors. 


The term TBI is applied to injuries caused by an external force or physical blow to the head. Major TBI causes include falls, assaults, motor vehicle accidents, gunshot wounds, child abuse, domestic violence, military actions (blast injuries), and workplace injuries. Injuries to the brain caused by rapid extreme acceleration and deceleration of the brain within the skull (as can occur in cyclist vs. motor vehicle events or “shaken baby syndrome”) are also Perspectives on Classification of Brain Injuries considered TBIs.


The use of these classifications can be helpful to healthcare professionals in understanding the causes of an individual’s brain injury and in considering which diagnostic tests and treatments will likely be most beneficial. In research settings, the use of the terms ABI and TBI may facilitate better-designed protocols and lead to more reliable and interpretable findings regarding causes, risk factors, and treatments. Further, the lay public may benefit from understanding the different signs and symptoms that indicate an ABI versus a TBI and may gain a better appreciation of the importance of seeking timely medical attention when these signs appear.


The use of the terms ABI and TBI have received criticism as well. Categorizations, broad as the terms ABI and TBI are, can lead to overgeneralizing the symptoms and outcomes of brain injuries. The unique nature of the brain injury that any individual suffers and the evolving nature of the short-term and long-term consequences of that injury should not be obscured by a label. Additionally, a degree of stigmatization can occur by applying these labels. This can also be the case when brain injury severity labels—mild, moderate, severe-are used early in the course of an individual’s brain injury and endure for a long time despite changes in the individual’s status. Further, some studies have shown inequities in access to services, supports, and resources across different brain injury categories. More specifically, funding for services and resources, particularly government funding, is sometimes more favorable for those diagnosed with TBI than those diagnosed with ABI.


The DLF recognizes that the use of the terms ABI and TBI has different implications in different contexts. This is true for the brain injury severity ratings (“mild,” “moderate,” and “severe”) as well. The idea that these labels may be more or less beneficial depending on context and the constituency group being addressed appears to be consistent with the stance taken by the Brain Injury Association of America. The DLF supports using the more general and simpler term “brain injury” in the context of dissemination of information, referral to resources, and advocating for individuals with brain injury and their families. However, as an organization that aspires to catalyze basic research into biomolecular medicines, technological advances, and other biomedical innovations that promote regeneration of the damaged brain, we recognize that classification and clear specification of research protocols are necessary for building a reliable and progressive knowledge base.

A man in a white lab coat and tie is standing in front of a blue background.
By Dan Lewis Foundation November 13, 2024
Stroke is a common neurological condition that damages brain cells (neurons) in the affected area, leading to a loss of the functions controlled by that region. A hopeful aspect of stroke recovery is that, over time and with rehabilitation, many individuals regain some abilities. This recovery has been linked to a process called “remapping,” where neurons in unaffected areas of the brain adapt to take over the functions of the damaged areas. Although many studies have explored this remapping phenomenon, most evidence has been indirect, based on changes in brain activation patterns or neuron connections after stroke in animal models. Direct proof that neurons change functionality after stroke has been lacking, partly because measuring neuron activity in the brain over time, especially at the necessary scale and duration, is challenging.
A man is holding a fish in his hand in front of a lake.
By Dan Lewis Foundation November 6, 2024
After a life-altering accident in October 2022, Devon Guffey’s story is about resilience and determination. His journey has been profiled in the summer 2023 issue of the Making Headway Newsletter: https://www.danlewisfoundation.org/devons-story . Hit by a drunk driver, Devon sustained severe brain and physical injuries, including axonal shearing, a traumatic frontal lobe injury, and facial fractures. Even after contracting meningitis while in a coma, Devon fought hard to survive – and today, his recovery continues to inspire us all. In late 2023, Devon worked as an assistant basketball coach at Blue River Valley, where he had once been a student. His love for sports and dedication to regaining his physical strength returned him to the gym, where his hard work paid off. Devon’s persistence earned him another job at the YMCA, guiding gym members and supporting facility upkeep. Through all the challenges—deafness in one ear, blindness in one eye, and a permanent loss of taste and smell—Devon perseveres. He recently regained his driving license, a significant milestone that symbolizes his increasing independence and cognitive and physical recovery. While each day may not show significant changes, Devon now sees his progress over time. Today, Devon speaks to groups about his journey, the dangers of drunk driving, and finding strength in adversity. His message is clear: recovery is a process, and sometimes, "can't" simply means "can't do it yet ." Every TBI is unique, and Devon’s story powerfully reminds us of the strength that comes from resilience and community. We are grateful to Devon for continuing to share his story and for his role in uplifting others facing difficult paths. His journey is a testament to the fact that we are stronger together. #BrainInjuryAwareness #DevonsJourney #Resilience #EndDrunkDriving #MakingHeadway
Share by: