Bella’s Story
Dan Lewis Foundation | Spring 2023

Bella’s Story

Though brain injuries usually lead to a range of physical, cognitive, and emotional issues, every person who incurs a brain injury experiences a unique set of symptoms as well as both short-term and longer-term outcomes. This is true whether the brain injury is classified as mild, moderate, or severe. Therefore, it is important to take every brain injury seriously and to get medical attention as soon as possible to prevent further damage and to improve outcomes. Bella Kellis, at age 14, experienced a traumatic brain injury. In her own words, Bella, now 16, shares her story. 

From a very young age, I believed that prioritizing education and developing self-discipline was the key to success. At just five years old, I’d already fallen head-over-heels in love with school, I loved acquiring knowledge about the world and experiencing everything I could. That thinking was abruptly changed and put on hold when I was fourteen and sustained a traumatic brain injury.


It was mid-summer at Lake Murry in 2020. I was fifteen feet up in a pine tree, ready to use the rope swing to jump into the water, but things did not go as planned. Instead, I fell directly onto my head at the foot of the lake. At the time, my dad understood the potential severity of the accident and rushed me to the doctor, but they simply glued my lip together and sent me home. I walked out of urgent care with minimal bruising and no stitches. They assumed I was okay because I showed no apparent external physical damage beyond a torn lip, but what they didn’t see or understand was that I walked out an entirely different person. I thought maybe all I needed was some sleep and I’d wake up to the person I was before, but I was terribly wrong. 

"I was unpredictable, defensive & exhausted. I felt out of control and I knew I was a different person."

My sophomore year of high school started differently. Following the accident, I had multiple weekly emotional breakdowns and could not handle stress. I returned to school and found it almost impossible to stay awake in class (narcolepsy: a rare long-term brain condition that can prevent a person from choosing when to wake or sleep). I had always easily juggled sports, straight-A academics, friends, and family. However, I could no longer read without developing an instant headache. I felt abnormal anger, sadness, and mood swings daily. Maintaining healthy relationships was almost impossible.

By the end of my sophomore year, I was unpredictable, defensive & exhausted. I felt out of control and I knew I was a different person. My family could not comprehend how the girl who memorized her multiplication tables at age five was the same person sobbing over algebra 2, refusing to identify as a “math person” ever again. All of us were bewildered by the change. I spent the last two years rebuilding my academics, relationships, attending doctor appointments and therapies. Working to rebuild the life I once had is a struggle. The traumatic brain injury temporarily paused my development and left me trying to achieve what had been so simple before. I still face many obstacles in my day-to-day life, but I am making great progress. I have worked hard to compensate for the effects of my condition. It is an ongoing journey with plenty of adaptations, but the process allows me to know myself better than ever before.

Of the many struggles caused by my injury, I found the most detrimental was my loss of identity. When you cannot live your life as the person you once were, life as you know it, changes. Losing trust in yourself affects every area of your life, especially interactions with others. How can you build a strong bond with another individual if you do not have one with yourself? How could one accomplish simple, everyday tasks like communicating and reasoning with another person when the ability to communicate with myself was poor? My traumatic brain injury triggered a loss of self and disadvantaged me in every area of my life, including social, family, and academic settings.


My traumatic brain injury has transformed my attitude toward my accomplishments. It was a glimpse of reality, a reality of a world where we all have an expiration date, and in a split second, you could lose everything you have worked so hard for. All that stays with us is our experiences and those of the individuals we have impacted throughout our lives. Therefore, we don’t have time to waste on mindless activities that aren’t making a difference or bringing joy to our lives. Given the age of my injury, “brain plasticity” has allowed for what I believe is a miraculous brain recovery. However, I recognize that everyone does not share that fortune. I aspire to one day alter society’s current treatment and understanding of brain trauma by making that the focus of my studies in college and career beyond.

A man is holding a fish in his hand in front of a lake.
By Dan Lewis Foundation November 6, 2024
After a life-altering accident in October 2022, Devon Guffey’s story is about resilience and determination. His journey has been profiled in the summer 2023 issue of the Making Headway Newsletter: https://www.danlewisfoundation.org/devons-story . Hit by a drunk driver, Devon sustained severe brain and physical injuries, including axonal shearing, a traumatic frontal lobe injury, and facial fractures. Even after contracting meningitis while in a coma, Devon fought hard to survive – and today, his recovery continues to inspire us all. In late 2023, Devon worked as an assistant basketball coach at Blue River Valley, where he had once been a student. His love for sports and dedication to regaining his physical strength returned him to the gym, where his hard work paid off. Devon’s persistence earned him another job at the YMCA, guiding gym members and supporting facility upkeep. Through all the challenges—deafness in one ear, blindness in one eye, and a permanent loss of taste and smell—Devon perseveres. He recently regained his driving license, a significant milestone that symbolizes his increasing independence and cognitive and physical recovery. While each day may not show significant changes, Devon now sees his progress over time. Today, Devon speaks to groups about his journey, the dangers of drunk driving, and finding strength in adversity. His message is clear: recovery is a process, and sometimes, "can't" simply means "can't do it yet ." Every TBI is unique, and Devon’s story powerfully reminds us of the strength that comes from resilience and community. We are grateful to Devon for continuing to share his story and for his role in uplifting others facing difficult paths. His journey is a testament to the fact that we are stronger together. #BrainInjuryAwareness #DevonsJourney #Resilience #EndDrunkDriving #MakingHeadway
A close up of a brain with a lot of cells and a purple background.
By Dan Lewis Foundation | Summer 2024 July 10, 2024
Scientists worldwide are working to find ways to stimulate healing and functional recovery after severe brain injuries. This work is driven by the desperate needs of persons who have suffered brain damage. It is inspired by the knowledge that the information required to create new brain cells, cause these cells to interconnect, and stimulate new learning is contained in our genome. Now that we can readily generate stem cells from adult tissue, we have access to the genomic program that can control all of the intricate details of brain tissue formation. A number of different research themes are being pursued productively. These include: (1) enabling injured neurons to self-repair (“axonal repair”) 1,2 ; (2) replacing damaged tissue by increasing the growth of new neurons (“neurogenesis”) 3-5 ; (3) transplanting new brain cells that are derived from a person’s own stem cells (“autologous cellular repletion”) 6-8 ; (4) stimulating the re-wiring of new or surviving tissue by encouraging the formation of new connections (“synaptogenesis”) 9,10 ; and (5) augmenting the function of a damaged brain by the use of bio-computational prostheses (“brain-computer interfaces”) 11,12 ; We’ve explored these themes in previous newsletters. The goal of stimulating meaningful brain regeneration is now sufficiently plausible that a large-scale, well-funded campaign needs to be funded to bring meaningful new therapies to patients within the foreseeable future. Here, we suggest a high-level outline of the research themes for such a campaign. A ‘moon shot’ program towards brain regeneration would leverage cutting-edge technologies in stem cell research, gene therapy, synaptic plasticity, neuronal repair, and brain-computer interfaces (BCIs) to develop innovative treatments for brain injuries and neurodegenerative diseases. These treatments would target the restoration of lost brain functions and improvement in the quality of life for individuals affected by severe brain injuries. This research agenda aims to catalyze serious discussion about creating a federal program with funding, organizational resources, and expert governance to enable brain regeneration in our lifetimes. Major Themes For a Brain Regeneration “Moon Shot” Program 1: Promote the formation of new neurons 1.1 Stimulate the brain to create new neurons 1.2 Create new neurons from patient-derived induced pluripotent stem cells to be transplanted back into the patient. Create new glial cells to support neurogenesis. 2: Stimulate new synaptic formation 2.1 Develop drugs that enhance synaptic plasticity and promote the formation of new synaptic connections 3: Stimulate self-repair of damaged neurons 3.1 Develop drugs that de-repress neurons and, thereby, enable axonal regrowth 4: Develop brain-computer interfaces (BCIs) for brain-injured patients 4.1: Develop and test BCIs that enable the brain to control behaviors or external devices and, thereby, augment or replace impaired functions. 4.2: Develop and test BCIs that can accelerate the training of remapped brain tissue in persons with brain injuries to optimize functional recovery. 4.3: Combine BCIs with other strategies (e.g., cell repletion, synaptogenesis, and enhanced plasticity) to accelerate adaptation and functional improvement. The proposed research themes can underpin targeted research to stimulate meaningful brain regeneration, offering new hope for patients with brain injuries and neurodegenerative diseases. While the scientific challenges are profound, there has been sufficient progress to justify substantial investment in brain regeneration research. Any such large-scale program will require coordinated collaborations among academic and commercial partners, skillful governance and management, and a shared sense of profound commitment to the goal. The recent pace of advances in cell biology, stem cell technology, bio-computational interfaces, and genomically targeting medicines suggests that large-scale investment will yield meaningful clinical advances toward brain regeneration after injury. With robust funding and skilled leadership, this comprehensive research agenda has a realistic potential to transform scientific breakthroughs into tangible medical therapies, offering hope to millions affected by brain damage.
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