Devon’s Story
Dan Lewis Foundation | Fall 2023

On October 7, 2022, I was nineteen years old and out with four friends for what we all thought would be a fun evening of partying with friends. Our group was about 20 seconds from arriving at the party when a teenage drunk driver hit us head-on in Indiana. The drunk driver’s alcohol level was more than twice the legal limit. I was the most critically injured of the group, suffering massive life-threatening head injuries and bleeding from my head that emergency medical technicians could not stop. Taken to the local hospital, it quickly became apparent that my life hung in the balance, and survival would hinge on transferring me to a major trauma center. I was quickly life-lined by helicopter to Indiana University Methodist Hospital, one of only four level-one trauma centers in the state, to treat my traumatic brain injuries (TBI). My family learned it was unlikely I would survive. For a month, I remained in a coma. I had broken multiple bones on my face and had two major brain injuries: severe axonal shearing and a frontal lobe injury. Axonal shearing occurs when the brain shifts rapidly inside the skull, and long fibers in the brain (axons) scrape against the skull’s hard bone, causing traumatic brain injury. Axonal shearing often results in a coma and can impact multiple brain areas, as in my case. My frontal lobe injury is often associated with muscle weakness on one side of the body, depression, memory, and attention problems, all experiences I had. While still in a coma, two weeks after admission to Methodist Hospital, I contracted meningitis, complicating my recovery. While I had no memory of the week before and for weeks after, I slowly regained consciousness. Once stabilized, I was transferred to the rehabilitation unit at the Rehabilitation Hospital of Indiana (RHI), where I remained for another month. At that time, I was wheelchair-bound, and it was unclear if I would ever walk again or regain my memory and attention skills. 

Before my accident, I secured a car salesman job at Ray Skillman in Indiana. I felt the job was a good fit and thought I had a promising career working as a car salesman. Outside of work, I always considered myself a serious athlete; I loved playing basketball, working out in the gym, and fishing as often as possible. My determination, fitness, and “athlete mentality” contributed to my survival and recovery. While my recovery, as viewed by my doctors, is nothing less than miraculous, I still have multiple residual problems that may or may not be resolved through therapy. As a result of the accident, I am deaf in my right ear, blind in my left eye, have right-sided tremors, poor balance, and periods of extreme cold chills even in hot weather.  One of the most serious challenges I faced as I began my recovery was the emotional turmoil and depression I experienced. I felt furious with friends and family when they tried to stop me from attempting activities I thought I could do. Eventually, I made peace with the problem when I realized those who cared most about me struggled with the “new” Devon. I gradually understood they were struggling too, and their concern that I “shouldn’t do” certain things was their way of showing they cared. I continue to attend group therapy with those who have also experienced TBI. Despite the challenges ahead, I am grateful for my recovery so far and hope to return to selling cars and playing basketball, goals that I believe are within reach. My doctors have told me that my attention and memory, two areas they would not have expected the degree of recovery I have achieved, are impressive and continue to improve.

I think that there are several positive outcomes from the accident. First, I hope to be able to share my fight for recovery with young people who have experienced similar problems. Next, I want to make others aware of the dangers of drunk driving. And finally, I believe I am a kinder, gentler person willing to reach out and support others dealing with complex problems. I believe God reached out and has a plan for me. 


Editor’s Note: Devon recently received notification that he was a nominee for patient of the year at the Rehabilitation Institute of Indiana. On September 18, 2023 Devon was chosen as Patient of the Year. We wish Devon all the best as he continues his journey towards recovery.

A gold trophy with a laurel wreath around it.
By Dan Lewis Foundation April 2, 2025
For the third consecutive year, the Dan Lewis Foundation for Brain Regeneration is proud to announce the DLF Prize competition. The 2025 DLF Prize, a $20,000 award, will recognize an outstanding early career scientist (2 to 5 years post-doc) conducting innovative research in neuroscience, pharmacology, or biotechnology. This prestigious prize honors researchers whose work aligns with the DLF mission to drive breakthroughs in neural regeneration and repair. The current research priorities of the DLF are: Pharmacological Reactivation of Neural Repair: Research into pharmacological methods of reactivating or augmenting synaptogenesis, neurogenesis or axonal repair. Cell-Based Cortical Repair: Investigating the potential of derived cortical neurons to restore function in damaged cortical regions. Transcriptomics of Neural Recovery: Characterizing transcriptomic profiles of cortical neurons in the recovery phase following brain injury to identify pathways that drive repair. Molecular Inhibitor Targeting: Advancing anti-sense oligonucleotides (ASO’s) or small-molecule therapeutics designed to downregulate inhibitors of neural regeneration in the cortex or spinal cord. Application for the 2025 DLF Prize can be made by going to our website— danlewisfoundation.org —and clicking on the Tab “ 2025 DLF Prize ”. This will bring you into the application portal. The application portal opened in March, 2025 and will remain open through May 31st. Once in the portal, you will find complete information about the DLF prize, eligibility requirements, and an application form which can be filled in and submitted online. The winner of the 2023 DLF Prize, Dr. Roy Maimon, continues his research indicating that downregulation of PTBP1, an RNA-binding protein, can convert glial cells into neurons in the adult brain (Maimon et al. 2024) .* Dr. Maimon, currently a post-doc at the University of California, San Diego is currently interviewing for a faculty position at several prominent neuroscience departments. The winner of the 2024 DLF Prize, Dr. William Zeiger is a physician-scientist in the Department of Neurology, Movement Disorders Division, at UCLA. Dr. Zeiger has expertise in interrogating neural circuits using a classic “lesional neurology” approach. He states, “Our lab remains focused on understanding how neural circuits become dysfunctional after lesions to the cortex and on investigating novel circuit-based approaches to reactivate and restore damaged cortex”. * Maimon, Roy, Carlos Chillon-Marinas, Sonia Vazquez-Sanchez, Colin Kern, Kresna Jenie, Kseniya Malukhina, Stephen Moore, et al. 2024. “Re-Activation of Neurogenic Niches in Aging Brain.” BioRxiv. https://doi.org/10.1101/2024.01.27.575940.
By Dan Lewis Foundation April 2, 2025
Alan was injured in 2021, at age 42. An art teacher in Lakewood, Colorado, Alan was riding his bicycle after school and was crossing at an intersection when a truck turned into the crosswalk area and hit him. Alan reports no memory of the event but has been told this is what happened. Alan says “My frontal lobe took the brunt of the impact, particularly the left frontal lobe”. Alan had a 2 ½ week stay at a nearby hospital where he, “re-learned to talk, to walk, and drink”-- although again he reports no memory of his stay there. Alan was then transferred to Craig Rehabilitation Hospital, in Englewood, Colorado. Alan says, “The only reason I knew I was at Craig is that I rolled over in bed and saw “Welcome to Craig” on the dry erase board.” During this stage of recovering, Alan repeatedly denied that he had been in an accident. Twice he tried to leave Craig on his own accord despite his wife’s and his therapists’ assurances that it was important for him to stay to recuperate from his injuries. Alan’s wife was 8 months pregnant at the time of his accident and gave birth to their son while Alan was an inpatient at Craig. Alan’s wife brought his newborn son to visit him days after the birth and Alan held him while sitting in his wheelchair, but Alan wistfully reports this is another thing he can’t remember. Alan reports that he still has significant difficulties with memory. Alan has also experienced several other neuropsychological difficulties. He states that for months after his injury, he could not experience emotion. “I could not laugh, I couldn’t cry.” Even after three years, his emotional experience is constricted. However, an emotion that is sometimes elevated is irritation and anger. Sometimes, dealing with people can be difficult because he may have temper flare-ups with little reason. This is something that Alan regrets and he is working hard with his neuropsychologist to improve the regulation of his emotions. Alan also has difficulty with organization, motivation, and distractibility. Earlier in his recovery, he had trouble sequencing and had difficulty carrying out personal and household routines. Alan has benefited greatly from therapy and his own hard work to make improvements in these areas. A chief reason that Alan works so hard in his recovery is so that he can be a good father to his son who is now almost 3 years old. He recognizes that it is important not to get frustrated when it seems that he can’t provide what his son wants or needs at a given moment. “I’m trying to raise my son the best I can…he’s at such a pivotal time in his life.” Alan’s financial situation was helped for a time by Social Security Disability Insurance payments but these payments ended. He is trying to get SSDI reinstated but the process of doing so is confusing and is taking a lot of time. Alan returned to work about 11 months ago at a liquor store (after about 2 years of not being able to work), the same store where he previously worked part time while teaching. He works in the wine department. “I sell wine and make recommendations.” When asked for advice to other brain injury survivors, Alan’s words were: “No matter how confused or upset you are or how frustrated you get, keep pressing on and moving forward because there is light at the end of the tunnel even though it may seem long. Keep moving forward and don’t give up no matter what anyone says to you”. Alan added that supports for individuals with brain injury are very important. He has found support groups, retreats, and seminars/events where brain injury survivors can share their experience to be very helpful. The volunteer work he does at Craig Hospital has been valuable for him. Alan is an inspiring individual. Despite having scarce memory of his accident and some confusion about the functional losses he has experienced, Alan has worked hard to make his recovery as complete as possible. He continues to work hard to progress and to express gratitude for those who have assisted him along the way.